Latest (501.V2) Coronavirus Mutation Was Discovered

Like any other pathogen, the novel coronavirus is constantly evolving in response to the hosts it infects. It’s a mutation that allowed the virus to jump species between animals and ultimately reach humans. At least, that’s what researchers think happened with the original strain that infected the first people.

SARS-CoV-2 continued to mutate after that, with scientists tracking those genetic changes closely. This is crucial because mutations can make a virus more infectious or dangerous and can hinder drug and vaccine research. Several notable novel coronavirus strains have been found so far. The D614G mutation is believed to be responsible for the current status of the pandemic.

A few days ago, UK health officials announced that another new coronavirus mutation was spreading rapidly in the south of the country. The strain featured 17 distinct genetic changes, most of them impacting the spike protein. One of them is called N501Y, affecting the receptor-binding motif of the spike protein, according to the UK COVID-19 Genomics Consortium. The mutation did not appear to cause more severe illness, according to public health officials.

Now, a few days later, South African authorities have reported another SARS-CoV-2 mutation that’s apparently driving the second wave in the country. South Africa is nearing 1 million infections, with more than 24,000 people having died of COVID-19 complications. The second wave started in mid-November, with the country registering more than 10,000 cases in a single day a few days ago. This appears to be the second wave’s local peak, but the case count might continue to climb.

The new strain seems to be more dangerous, causing more severe illness in younger patients who do not suffer from other medical conditions.

Worldwide Panic On New Deadly Virus

The Centers for Disease Control and Prevention (CDC) on Thursday warned state and local health officials about potential infections from a deadly virus previously unseen in humans that has now sickened 14 people and killed 8.

A Generic Coronavirus

Most of the infections have occurred in the Middle East, but a new analysis of three confirmed infections in Britain suggests the virus can pass from person to person rather than from animal to humans, the CDC said in its Weekly Morbidity and Mortality Report on Thursday.

The virus is a coronavirus, part of the same family of viruses as the common cold and the deadly outbreak of Severe Acute Respiratory Syndrome (SARS) that first emerged in Asia in 2003. The new virus is not the same as SARS, but like the SARS virus, it is similar to those found in bats.

So far, no cases have been reported in the United States.

According to the CDC's analysis, the infections in Britain started with a 60-year-old man who had recently traveled to Pakistan and Saudi Arabia and developed a respiratory illness on January 24, 2013. Samples from the man showed he was infected with both the new virus and with H1N1, or swine flu.

This man subsequently passed the infection to two members of his household: a male with an underlying illness who became ill on February 6 and subsequently died; and a healthy adult female in his household who developed a respiratory illness on February 5, but who did not need to be hospitalized and has recovered.

The CDC said people who develop a severe acute lower respiratory illness within 10 days of returning from the Arabian Peninsula or neighboring countries should continue to be evaluated according to current guidelines.

The health agency said doctors should be watchful of patients who develop an unexplained respiratory infection within 10 days of traveling from the Arabian Peninsula or neighboring countries. The CDC has set up a special website with updates on the infections at http://www.cdc.gov/coronavirus/ncv/ .

Symptoms of infection with this new virus include severe acute respiratory illness with fever, cough and shortness of breath. Neither the CDC nor the World Health Organization has issued travel restrictions related to the virus.